The 2022 invasion of Ukraine degraded pre-existing public health surveillance and response capacities at national and regional levels and created additional public health threats. To support immediate public health needs and ongoing recovery efforts in Ukraine, ICAP is collaborating with the U.S. Centers for Disease Control and Prevention (CDC) to provide technical assistance to Ukraine’s public health system. The priority areas ICAP addresses include antimicrobial resistance response (AMR) prevention detection and response, respiratory disease surveillance, wastewater surveillance for SARS-CoV-2 and other major health threats, and laboratory response network strengthening for emergency preparedness and response.